Longitudinal evaluation of T1ρ and T2 spatial distribution in osteoarthritic and healthy medial knee cartilage
نویسندگان
چکیده
منابع مشابه
Knee Cartilage Thickness, T1ρ and T2 Relaxation Time Are Related to Articular Cartilage Loading in Healthy Adults
Cartilage is responsive to the loading imposed during cyclic routine activities. However, the local relation between cartilage in terms of thickness distribution and biochemical composition and the local contact pressure during walking has not been established. The objective of this study was to evaluate the relation between cartilage thickness, proteoglycan and collagen concentration in the kn...
متن کاملComparison of T1ρ, T2 mapping, and sodium MRI of osteoarthritic cartilage in vivo
M. A. Vogelsong, E. Staroswiecki, B. A. Hargreaves, E. Han, J. A. Fattor, A. L. Friedlander, O. Shah, J. M. Beaubien, and G. E. Gold Radiology, Stanford University, Stanford, CA, United States, Electrical Engineering, Stanford University, Stanford, CA, Radiology, Stanford University, Stanford, CA, GE Healthcare Global Applied Sciences Laboratory, Menlo Park, CA, Stanford Center on Longevity, St...
متن کاملT1ρ/T2 mapping and histopathology of degenerative cartilage in advanced knee osteoarthritis
AIM To investigate whether normal thickness cartilage in osteoarthritic knees demonstrate depletion of proteoglycan or collagen content compared to healthy knees. METHODS Magnetic resonance (MR) images were acquired from 5 subjects scheduled for total knee arthroplasty (TKA) (mean age 70 years) and 20 young healthy control subjects without knee pain (mean age 28.9 years). MR images of T1ρ map...
متن کاملSpatial variation in cartilage T2 of the knee.
Technical limitations imposed by resolution and B1 homogeneity have thus far limited quantitative in vivo T2 mapping of cartilage to the patella. The purpose of this study is to develop T2 mapping of the femoral/tibial joint and assess regional variability of cartilage T2 in the knee. Quantitative in vivo T2 mapping of the knee was performed on 15 asymptomatic adults (age, 22-44) using a 3T MR ...
متن کاملLocalized inter-subject comparison of knee cartilage thickness, T2 and T1ρ: generating an atlas of the knee
Introduction and Motivation. In osteoarthritis of the knee (knee OA), different morphological, molecular, and biochemical biomarkers for predicting or evaluating the degree of knee OA have been investigated. It has been observed that with progression of knee OA morphometric parameters such as cartilage thickness and volume decrease; and that molecular and biochemical cartilage properties such a...
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ژورنال
عنوان ژورنال: Osteoarthritis and Cartilage
سال: 2014
ISSN: 1063-4584
DOI: 10.1016/j.joca.2013.10.014